Histoid leprosy is a skin condition, a rare form of multibacillary leprosy See also. Leprosy · Skin lesion. References. ^ James, William D.; Berger. Histoid leprosy, an uncommon variant of lepromatous leprosy, develops usually as relapse in lepromatous patients who are on dapsone. Summary Histoid leprosy is a rare multibacillary form that presents with disseminated papule-nodular cutaneous lesions. To study the inflammatory infiltrate.
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Multiple, well-defined, erythematous nodules and papules present over the back and neck Click here to view. Dermis showed diffuse collection of foamy macrophages and spindle shaped cells histiocytes Click here to view.
Lepromatous leprosy of histoid type Annigeri S R, Metgud S C, Patil J R – Indian J Med Microbiol
Retrieved from ” https: Tuberculoid leprosy Borderline tuberculoid leprosy Borderline leprosy Borderline lepromatous leprosy Lepromatous leprosy Histoid leprosy. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Histoid leprosy is known to occur in patients on anti — leprosy treatment or as a variant of lepromatous leprosy. Report from so-called nonendemic areas.
Footnotes Source of support: In India, its incidence among leprosy patients has been estimated to be between 2. They have been reported in patients of age 10 — 84 years.
Histoid leprosy is an uncommon variant of lepromatous leprosy with characteristic clinical, immunologic, and bacteriologic findings. It is a variant of lepromatous leprosy. Sehgal VN, Srivastava G.
Adriano Piris, Alice Z. Slit skin smear from the histoid lesions show abundant acid-fast bacilli in clusters, singles or tightly packed in macrophages. Histoid, a clinical variant of multibacillary leprosy: Int J Lepr ; Histoid leprosy might represent an enhanced response of the multibacillary disease in localizing the disease process.
The authors would like to acknowledge and thank Dr. Abstract Histoid leprosy is an uncommon entity with specific clinical, histopathological and bacteriological features. It exhibits a fibromatoid tendency in the chronic form.
Leprosy relapse presenting in histoid form after MDT. Continual occurrence of these cases does not bode well for a country like India, where leprosy was eliminated as a public health problem in Photomicrograph showing epidermal atrophy and grenz zone.
De-novo Histoid Leprosy
Indian J Med Microbiol. Multiple, well-defined, erythematous nodules and papules present over the abdomen and chest Click here to view.
Histoid hsitoid HLinitially described by Wade, is considered by some as a variant of lepromatous leprosy LL ,and by others as distinct entity.
Dermatol Online J ; How to cite this URL: They are considered as mutant bacilli resulting from drug resistance. The AFB are not found in globi formation, as they do not secrete any glial substance. The dermis revealed a large, circumscribed collection of peprosy spindle cells resembling fibroblasts, arranged in a whorled and storiform pattern, with entrapped but preserved small dermal nerve and adenexal structures.
The spindled histiocytes resemble fibroblasts and it hietoid suggested that these fibroblast-like macrophages may have arisen from tissue histiocytes rather than from blood monocytes [ 9 ].
This form of leprosy is fairly common in patients on dapsone monotherapy and irregular treatment.